Protein Modification Reagents
GENOVIS INC FABRICATOR IGG PROTEASE, 5000U
Detailed Information aEFabRICaTOR digests IgG only at one specific site just below the hinge region, resulting in F(ab')2and Fc-fragments. Since FabRICaTOR only cleaves at one specific site below the hinge region, there is no risk of over digestion if the incubation time is increased for several hours. FabRICaTOR digests IgG under physiological reaction conditions thus preserving the immunoreactivity. Best activity is obtained at 37a Deg. C but digestion can also be performed at room temperature using prolonged reaction time. SpeciesFabRICaTOR digests all subclasses of human, monkey, rabbit and sheep IgG. FabRICaTOR has limited activity on mouse IgG2a and IgG3 and for digestion of mouse IgG2a and IgG3 the use of FabRICaTOR Z is recommended.Follow this link to view a protease IgG digestion chart with species StabilityThe enzyme is reconstituted by addition of water and after reconstitution FabRICaT
Sigma Aldrich Fine Chemicals Biosciences Endoproteinase Lys-C Sequencing Grade, 3 X 5 μg
Endoproteinase Lys-C Sequencing Grade is isolated from Lysobacter enzymogenes as a highly purified and specific protease.
Creative Pegworks PSB-451 4-Arm PEG-MAL, MW 10k, 10 grams
4-Arm PEG-MAL is a multiarmed PEG derivative with maleimide at each terminal of the four arms connected to one pentaerythritol core. Maleimide selectively reacts with free thiol, SH, sulfhydryl, or mercapto group via Michael addition to form a stable thioether bond. PEG-MAL useful for site specific protein and peptide modification. Hydroquinone MEHQ at ~ 200 ppm may be present as inhibitors to prevent self polymerization and partial crosslinking. MEHQ may be removed per customer request.
eMolecules 2140807-17-4 | Medchem Express | Pomalidomide-PEG2-COOH | 25mg | 633697027 | HY-131872 | 433.417 | C20H23N3O8
Ambeed | 26-Difluoro-4-formylbenzonitrile | 250mg | 521442519 | A455727 | 433939-88-9 | MFCD09263470 | 167.115 | C8H3F2NO
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Peg5-tos | 155130-15-7 | 96.9% | 392.46 | 500 MG
PEG5-Tos is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs work by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand and a target protein ligand via a linker.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Facilitates selective degradation of target proteins.
Medchemexpress LLC Acetic acid, 2-[2-(2-aminoethoxy)ethoxy]- | 134978-97-5 | 163.17 | 5 G
H2N-PEG2-CH2COOH is a PEG-based PROTAC linker, appearing as a white to yellow solid. This compound can be utilized in the synthesis of PROTACs, which are molecular tools composed of two distinct ligands joined by a linker. One ligand binds to an E3 ubiquitin ligase, and the other targets a protein of interest, allowing PROTACs to leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- White to yellow solid appearance
- High purity (99.87%)
Thermo Scientific Production Chemicals and Services DOE AND INGALLS
NC3999733 TCEP HCL CGMP 1-GM FRZ
Bioss Sphingosine Kinase 1 C-termin
Sphingosine Kinase 1 (C-terminal region) Primary Antibody Unconjugated Host Species Rat Target Species Human Mouse Rat Clonality Monoclonal Applications WB M540Concentration Size 100 ul Storage Buffer PBS 1 mg/ml BSA 0 05% NaN3 and 50% glycerol
Medchemexpress LLC Nε-(carboxyethyl)lysine-d4 | MFCD30364298 | 98.0% | 222.27 g/mol | C9H14D4N2O4 | 1 MG
Nε-(Carboxyethyl)lysine-d4 is a deuterium-labeled (d4) isotopic analogue of Nε-(carboxyethyl)lysine used as an internal standard for quantitative mass spectrometry and tracer studies. Supplied in small milligram quantities for analytical calibration, it supports accurate measurement of advanced glycation endproducts; consult the certificate of analysis for lot-specific purity, storage, and handling.
- Deuterium-labeled (d4) isotopic internal standard for mass spectrometry.
- Supplied in small, ready-to-use quantities suitable for trace analysis.
- Facilitates accurate quantitation of advanced glycation endproducts (AGEs).
- Compatible with common sample preparation and LC-MS workflows.
- Chemical formula C9H14D4N2O4 and molecular weight ~222.27 g/mol.
- Refer to the certificate of analysis for purity and storage details.